Hydration
cerabone® granules can be applied dry or wet. Hydration in blood or sterile saline solution facilitate the handling and application of the granules, as they adhere to each other

Compacting of the granules
To provide space for the regenerative process only gentle compression of the granules is recommended. It allows for revascularization and osseointegration of the bone grafting particles by the three-dimensional pore network of cerabone®.

Stabilization of the granules
The cerabone® granules should always be covered by a membrane in order to immobilize the particles at the augmented site and to prevent soft tissue ingrowth into the bone defect. When treating defects outside the ridge contour, a fixation of the membrane by pins or screws can be advantageous.

Healing time and re-entry
A healing time of at least 6 months is recommended before re-entry to ensure stable integration of the particles.

Mixing with autograft
Mixing of cerabone® with autologous bone adds a biological activity (osteoinductive and osteogenetic properties of autologous bone) and supports faster regeneration and improved formation of new bone.

Mixing with allograft (maxgraft®)
Mixing of cerabone® with allogeneic bone (maxgraft®) combines the advantages of both materials; the biological potential of maxgraft® and the long-term stability of cerabone® lead to fast regeneration of vital, strong bone.